Fakan F, Skálová A, Michal M
Siklův patologicko-anatomický ústav LF UK, Plzen.
Cesk Patol. 1994 Feb;30(1):3-7.
Two distinct morphological types of malignant lymphoma in the same patient occur mostly due to transformation of a low-grade lymphoma to high-grade lymphoma. When two morphologically different structures are found at different sites they represent discordant lymphoma. Composite lymphoma, on the other hand, shows two histologic subtypes involving the same location. Bimorphic morphology of malignant lymphoma is of therapeutic and prognostic significance.
同一患者出现两种不同形态学类型的恶性淋巴瘤,大多是由于低度淋巴瘤向高度淋巴瘤转化所致。当在不同部位发现两种形态不同的结构时,它们代表不一致性淋巴瘤。另一方面,复合性淋巴瘤表现为涉及同一部位的两种组织学亚型。恶性淋巴瘤的双形态形态学具有治疗和预后意义。