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小鼠下丘脑细胞构筑图谱。

A cytoarchitectonic atlas of the mouse hypothalamus.

作者信息

Broadwell R D, Bleier R

出版信息

J Comp Neurol. 1976 Jun 1;167(3):315-39. doi: 10.1002/cne.901670304.

DOI:10.1002/cne.901670304
PMID:818133
Abstract

A description of the organization, areas, and cell groups within the hypothalamus of the mouse is presented in detail. Photomicrographs of cell-stained serial sections through the hypothalamus in frontal, sagittal and horizontal planes are included. The hypothalamus has been divided basically into medial and lateral parts with most well-defined cell groups or nuclei lying within the medial subdivision and surrounded by diffuse collections of cells referred to as areas. The heterogenetiy of cell types within most hypothalamic nuclei and areas has been emphasized with the consequent implications for heterogeneity of neuronal connections and of functions. Recently introduced neuroanatomical techniques permitting increased attention to the cellular level of organization have demonstrated precise connections and functional localization of cells within the hypothalamus. While cytoarchitectonic distinctions imply functional distinctions, morphological and experimental evidence suggest the existence also of systems of cells which transcend conventional cytoarchitectonic boundaries, the cells within each system being interconnected functionally or neuronally.

摘要

本文详细介绍了小鼠下丘脑内的组织结构、区域和细胞群。文中包含了下丘脑在额面、矢状面和水平面的细胞染色连续切片的显微照片。下丘脑基本分为内侧和外侧两部分,大多数明确的细胞群或核位于内侧分区内,并被称为区域的弥漫性细胞集合所包围。大多数下丘脑核和区域内细胞类型的异质性已得到强调,这对神经元连接和功能的异质性具有相应影响。最近引入的神经解剖技术使人们能够更多地关注细胞组织水平,这些技术已证明下丘脑内细胞的精确连接和功能定位。虽然细胞结构上的差异意味着功能上的差异,但形态学和实验证据表明,也存在超越传统细胞结构边界的细胞系统,每个系统内的细胞在功能上或神经元上相互连接。

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