Sanchis V, Vinas I, Roberts I N, Jeenes D J, Watson A J, Archer D B
Institute of Food Research, Norwich Research Park, Colney, UK.
FEMS Microbiol Lett. 1994 Apr 1;117(2):207-10. doi: 10.1111/j.1574-6968.1994.tb06766.x.
A gene encoding a putative pyruvate decarboxylase (EC 4.1.1.1) was isolated from a genomic library of the filamentous fungus Aspergillus parasiticus strain SU-1. The deduced amino acid sequence showed 37% homology to PDC1 from Saccharomyces cerevisiae. Although A. parasiticus has an obligate growth requirement for oxygen, it produced ethanol in shake flask cultures indicating a response to anoxic conditions mediated by pyruvate decarboxylase.