Haltenhof H, Schröter C
Psychiatrische Klinik mit Poliklinik, Philipps-Universität Marburg.
Fortschr Neurol Psychiatr. 1994 Mar;62(3):94-101. doi: 10.1055/s-2007-996660.
Depressive disorders occur in Parkinson's disease in about 40%. They often manifest--not seldom preceding diagnosis of Parkinson's syndrome--like monopolar depression. Their cause has not yet been explained in a satisfactory way. Neurotransmitter disturbances are discussed as well as psychogenic factors. There seems to be a subtype of Parkinson's disease with more frequent depression, which is characterized by increased rigidity and bradykinesia, lower age at onset and family history of Parkinson's disease. Especially antidepressants, but also sleep deprivation and electroconvulsive therapy are efficient. The review is illustrated by a case report.
帕金森病患者中约40%会出现抑郁症。它们常常表现为——并不罕见地在帕金森综合征诊断之前出现——像单相抑郁症一样。其病因尚未得到令人满意的解释。人们讨论了神经递质紊乱以及心理因素。似乎存在一种帕金森病亚型，抑郁症更为常见，其特征是僵硬和运动迟缓加剧、发病年龄较低以及有帕金森病家族史。特别是抗抑郁药，但睡眠剥夺和电休克疗法也有效。本文通过一个病例报告来说明这一综述。
