人和小鼠酪氨酸酶之间的免疫交叉反应。
Immunologic cross-reaction between human and mouse tyrosinases.
作者信息
Ohtaki N, Miyazaki K
出版信息
J Invest Dermatol. 1976 May;66(5):327-9. doi: 10.1111/1523-1747.ep12482305.
PMID:818320
Abstract
Human tyrosinase, partially purified from metastatic malignant melanoma, reacted with antiserum prepared against tyrosinase purified from Harding-Passey mouse melanoma melanosomes, although the human and mouse tyrosinases were not completely identical immunologically. The human tyrosinae showed only one band on disc electrophoresis which corresponded in mobility to T2 tyrosinase of mouse.
摘要
从转移性恶性黑色素瘤中部分纯化得到的人酪氨酸酶，与针对从哈丁 - 帕西小鼠黑色素瘤黑素小体中纯化的酪氨酸酶制备的抗血清发生反应，尽管人和小鼠的酪氨酸酶在免疫学上并不完全相同。人酪氨酸酶在圆盘电泳上仅显示一条带，其迁移率与小鼠的T2酪氨酸酶相对应。
Zotero 插件