Mannes G P, de Boer W J, van der Bij W, Grevink R G, Koëter G H
Afd. Longziekten, Academisch Ziekenhuis, Groningen.
Ned Tijdschr Geneeskd. 1994 Apr 16;138(16):808-12.
To analyse the selection and outcome in patients placed on the waiting list for lung transplantation in Groningen.
Retrospective and descriptive.
University Hospital Groningen.
Clinical lung transplantations have been performed at Groningen University Hospital since November 1990. Until the beginning of August 1993 over 200 patients were presented. Patients' eligibility for lung transplantation was evaluated according to a fixed protocol.
Seventy patients were placed on the waiting list. Indications for lung transplantation were cystic fibrosis (22 patients), COPD/emphysema (24), pulmonary hypertension (14), pulmonary fibrosis (7), and another diagnosis (2). One patient required a second transplantation. Thirty patients underwent a transplantation after an average waiting period of 6.3 months. Eleven patients died on the waiting list, after an average waiting period of 3.9 months. The highest mortality on the waiting list concerned patients with cystic fibrosis. Characteristics and evolution on the waiting list of the selected patients were in accordance with the literature.
The growing number of candidates for lung transplantation is increasing the shortage of suitable donor lungs. A successful lung transplantation programme necessitates expansion of the donor potential, as well as meticulous selection of candidates.
分析格罗宁根地区肺移植等待名单上患者的选择情况及预后。
回顾性和描述性研究。
格罗宁根大学医院。
自1990年11月起，格罗宁根大学医院开展了临床肺移植手术。截至1993年8月初，有超过200名患者前来就诊。根据固定方案评估患者的肺移植资格。
70名患者被列入等待名单。肺移植的适应证包括囊性纤维化（22例）、慢性阻塞性肺疾病/肺气肿（24例）、肺动脉高压（14例）、肺纤维化（7例）以及其他诊断（2例）。1例患者需要进行二次移植。30例患者在平均等待6.3个月后接受了移植手术。11例患者在等待名单上死亡，平均等待时间为3.9个月。等待名单上死亡率最高的是囊性纤维化患者。所选患者在等待名单上的特征和病情发展与文献相符。
肺移植候选者数量的增加加剧了合适供体肺的短缺。成功的肺移植项目需要扩大供体来源，并对候选者进行细致筛选。
