Nomura N, Yamada A, Saitou F, Tsuzawa T, Yamashita I, Sakakibara T, Shimizu T, Sakamoto T, Karaki Y, Tazawa K
Second Dept. of Surgery, Toyama Medical and Pharmaceutical University.
Gan To Kagaku Ryoho. 1994 May;21(6):865-8.
A 54-year-old man was diagnosed with Borr 1 type gastric cancer, located just below ECJ with some paraaortic lymph node metastase, during treatment of diabetes mellitus at another hospital. He underwent spleno-total gastrectomy for reduction. The metastatic lymph nodes of the para-aorta were not resected, so the surgery was considered palliative. We administered FTP chemotherapy (CDDP 110 mg/day 1, 5-FU 1,200 mg/day 1-5, THP-ADM 30 mg/day 1) 5 times following surgery. The metastatic lymph nodes were remarkably decreased in size by the initial treatment. The decrement was 52.4% after the initial treatment (PR). After the 4th treatment, there were no lymph nodes detected (CR). After the 5th treatment, CR continued. The PR period was considered to be 5 months, and that of CR 4 months. The patient has no renal or heart dysfunction, and no suppression of bone marrow. His quality of life is satisfactory, and he continues to work as prior to surgery. FTP chemotherapy is considered a successful regimen for postoperative chemotherapy.
一名54岁男性在另一家医院治疗糖尿病期间被诊断为Borrmann 1型胃癌，位于食管胃交界下方，伴有一些主动脉旁淋巴结转移。他接受了脾全切胃切除术以缓解病情。主动脉旁的转移淋巴结未切除，因此该手术被认为是姑息性的。术后我们给予FTP化疗（顺铂110mg/天，第1天；5-氟尿嘧啶1200mg/天，第1 - 5天；吡柔比星30mg/天，第1天）5次。初始治疗后转移淋巴结大小显著减小。初始治疗后缩小率为52.4%（部分缓解）。第4次治疗后，未检测到淋巴结（完全缓解）。第5次治疗后，完全缓解持续存在。部分缓解期被认为是5个月，完全缓解期为4个月。患者没有肾或心脏功能障碍，也没有骨髓抑制。他的生活质量令人满意，继续像手术前一样工作。FTP化疗被认为是术后化疗的成功方案。
