Kunst H
MMW Munch Med Wochenschr. 1976 May 21;118(21):683-6.
No fundamental change in the pathogen spectrum of purulent meningitis in adults has occurred between 1951 and 1974. It should be noted, however, that there is an increase in gram-negative pathogens. The lethality has in fact decreased during the period of observation, but the prognosis of pneumococcal meningitis has not been decisively improved by high dosage therapy with penicillin or ampicillin.
1951年至1974年间,成人化脓性脑膜炎的病原体谱没有发生根本性变化。然而,应该注意的是,革兰氏阴性病原体有所增加。实际上,在观察期内致死率有所下降,但青霉素或氨苄青霉素高剂量治疗并未显著改善肺炎球菌性脑膜炎的预后。