Espí Macías A, Sales Maicas A, Marti Cuñat E, Caballero Garate A
Departamento de Cirugía, Hospital Clínico, Facultad de Medicina, Valencia.
Rev Esp Enferm Dig. 1994 Feb;85(2):123-6.
A psammomatous endocrine tumor of the duodenum associated with a perforated duodenal ulcer, acute diffuse peritonitis and multiple organ failure is described. Histologic evaluation of the tumor shows a mixed pattern, with solid and glandular structures. Immunohistochemical stains further show cytoplasmic storage of gastrin and somatostatin. Apical CEA staining is also demonstrated in glandular areas of the tumor.
本文描述了一例十二指肠砂粒体性内分泌肿瘤,伴有十二指肠溃疡穿孔、急性弥漫性腹膜炎和多器官功能衰竭。肿瘤的组织学评估显示为混合模式,具有实性和腺性结构。免疫组化染色进一步显示胃泌素和生长抑素的细胞质储存。肿瘤腺性区域也显示顶端癌胚抗原染色。