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法国东南部的HIV产前筛查:不同妊娠结局的血清流行率及筛查政策差异

HIV prenatal screening in south-eastern France: differences in seroprevalence and screening policies by pregnancy outcome.

作者信息

Obadia Y, Rey D, Moatti J P, Pradier C, Couturier E, Brossard Y, Brunet J B

机构信息

South-Eastern France Regional Center for Disease Control, ORS PACA, Marseille.

出版信息

AIDS Care. 1994;6(1):29-38. doi: 10.1080/09540129408258022.

Abstract

Two complementary surveys were carried out in the 89 hospital units of South-Eastern France which deal with pregnant women. Firstly, in November 1991, medical chiefs of these units were interviewed face-to-face about their current HIV screening policy. Secondly, between Jan 27 and March 22, 1992, all women at the end of their pregnancy attending these units were included in an anonymous unlinked seroprevalence survey, irrespective of pregnancy outcome (n = 11,056). The goal of the research was to compare HIV prenatal screening policies and seroprevalences by pregnancy outcomes in order to contribute to the public debate initiated on that issue by the French health authorities. The seroprevalence survey showed a global prevalence rate of 0.43% (CI 95% = 0.32-0.54) with the prevalence among women who had an elective abortion (0.56%) being more than twice that among women who delivered (0.22%). However, routine HIV screening was more frequent toward women coming for regular prenatal care than for women seeking abortion. A systematic procedure for obtaining women's consent for HIV testing only existed in a minority of units. Only 23 out of the 62 units offering both antenatal and termination services to women had the same screening policy for women attending the different services. The research confirmed that a mandatory requirement would not improve HIV screening policy during prenatal care. However, less emphasis on women who have opted for termination of pregnancy, an absence of appropriate counselling and information procedures, and pressures on HIV-infected women to terminate current pregnancies and discourage future ones strongly suggest that HIV prenatal screening in French hospitals remains mainly focussed on fetal concerns, without sufficient attention towards the needs of women at risk of HIV infection.

摘要

在法国东南部负责处理孕妇问题的89个医院科室开展了两项互补性调查。首先,1991年11月,对这些科室的医务主任进行了面对面访谈,了解他们当前的艾滋病毒筛查政策。其次,在1992年1月27日至3月22日期间,所有在这些科室就诊的妊娠晚期妇女都被纳入一项匿名非关联血清流行率调查,无论妊娠结局如何(n = 11,056)。该研究的目的是比较艾滋病毒产前筛查政策以及不同妊娠结局的血清流行率,以便为法国卫生当局发起的关于该问题的公众辩论提供参考。血清流行率调查显示总体流行率为0.43%(95%置信区间 = 0.32 - 0.54),其中选择性堕胎妇女的流行率(0.56%)是分娩妇女流行率(0.22%)的两倍多。然而,针对定期接受产前检查的妇女进行常规艾滋病毒筛查的频率高于寻求堕胎的妇女。只有少数科室存在获取妇女同意进行艾滋病毒检测的系统程序。在为妇女提供产前和终止妊娠服务的62个科室中,只有23个科室对接受不同服务的妇女采用相同的筛查政策。该研究证实,强制要求并不会改善产前护理期间的艾滋病毒筛查政策。然而,对选择终止妊娠的妇女关注较少、缺乏适当的咨询和信息程序,以及对感染艾滋病毒的妇女施加压力要求其终止当前妊娠并避免未来怀孕,这些都强烈表明法国医院的艾滋病毒产前筛查主要仍集中在胎儿方面,而没有充分关注感染艾滋病毒风险妇女的需求。

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