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手术风险增加患者胆总管结石的体外冲击波碎石术

Extracorporeal shock wave lithotripsy of common bile duct stones in patients with increased operative risk.

作者信息

van der Hul R L, Plaisier P W, van Blankenstein M, Terpstra O T, den Toom R, Bruining H A

机构信息

Department of Surgery, University Hospital Rotterdam, The Netherlands.

出版信息

Eur J Surg. 1994 Jan;160(1):31-5.

PMID:8186311
Abstract

OBJECTIVE

Assessment of efficacy of extracorporeal shock wave lithotripsy (ESWL) of stones in the common bile duct.

DESIGN

Prospective clinical study.

SETTING

Department of Surgery, University Hospital Rotterdam, Rotterdam, The Netherlands.

SUBJECTS

90 patients with stones in the common bile duct and at increased operative risk (median age 73 years, range 27-95).

INTERVENTIONS

After failure of endoscopic measures, the first 13 patients were treated under general anaesthesia with a first generation lithotriptor. Of the next 77 patients, treated with a second generation lithotriptor, only one required general anaesthesia and 68 intravenous analgesia and sedation. Eight patients needed no analgesia at all.

MAIN OUTCOME MEASURES

Fragmentation, clearance, and recurrence of stones.

RESULTS

Fragmentation of stones was achieved in all the first 13 patients and 63 of the 90 patients (69%). There were minor complications (macroscopic haematuria and subcapsular haematoma of the right kidney) in 13 and serious complications (bacteraemia) in 2. At follow-up (median 28 months), 2 patients had recurrent stones.

CONCLUSION

ESWL of stones in the common bile duct is safe and effective and should be considered in high risk patients.

摘要

目的

评估体外冲击波碎石术(ESWL)治疗胆总管结石的疗效。

设计

前瞻性临床研究。

地点

荷兰鹿特丹大学医院外科。

研究对象

90例胆总管结石且手术风险增加的患者(中位年龄73岁,范围27 - 95岁)。

干预措施

在内镜治疗失败后,前13例患者在全身麻醉下使用第一代碎石机进行治疗。在接下来的77例使用第二代碎石机治疗的患者中,只有1例需要全身麻醉,68例需要静脉镇痛和镇静。8例患者根本不需要镇痛。

主要观察指标

结石的破碎、清除及复发情况。

结果

前13例患者以及90例患者中的63例(69%)结石被破碎。13例出现轻微并发症(肉眼血尿和右肾包膜下血肿),2例出现严重并发症(菌血症)。随访(中位时间28个月)时,2例患者出现结石复发。

结论

胆总管结石的体外冲击波碎石术安全有效,高危患者应考虑采用该治疗方法。

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