Kratzer W, Mason R A, Grammer S, Preclik G, Beckh K, Adler G
Department of Internal Medicine I, University Clinic of Ulm, Germany.
Hepatogastroenterology. 1998 Jul-Aug;45(22):910-6.
BACKGROUND/AIMS: In a prospective study, we investigated stone recurrence in high risk patients with difficult common bile duct stones treated with extracorporeal shockwave lithotripsy (ESWL) after futile endoscopic attempts at stone extraction with sphincterotomy.
Endoscopic stone extraction proved unsuccessful in 35 of 659 patients presenting with common bile duct stones (5.5%, 11 males and 24 females: mean age 71.0+/-10.0 yrs; BMI 25.8+/-3.9; ASA-Classification 2.63+/-0.65), due to large stone size (10 patients), incarcerated stones (15 patients), stones inaccessible to the Dormia basket (7 patients) or an impacted Dormia basket (3 patients). The stones were localized radiologically. ESWL was performed using the HM3 lithotripter (Dornier, Munich/FRG).
Immediately following ESWL, 17.1% of the patients treated showed complete stone clearance. In an additional 57.1%, further endoscopic stone extraction was required to achieve complete stone clearance, while 20.0% were discharged with small residual stone fragments. The remaining 2 patients (5.7%) required surgical intervention. Thirty four of 35 patients (97.1%) were followed-up for an average of 27+/-11 months. Five patients (14.3%) experienced stone recurrence at an average of 13.8+/-5.7 months post ESWL.
ESWL is a useful and safe adjunct to endoscopic management of difficult common bile duct stones in older, high-risk patients. The stone recurrence rate was about 14% after one year. All recurrent stones were treatable by endoscopy.
背景/目的:在一项前瞻性研究中,我们调查了经内镜括约肌切开取石术失败后,采用体外冲击波碎石术(ESWL)治疗的高危胆总管结石患者的结石复发情况。
659例胆总管结石患者中,35例(5.5%,男性11例,女性24例:平均年龄71.0±10.0岁;体重指数25.8±3.9;美国麻醉医师协会分级2.63±0.65)经内镜取石失败,原因包括结石体积大(10例)、嵌顿性结石(15例)、Dormia网篮无法触及的结石(7例)或Dormia网篮嵌顿(3例)。通过放射学方法对结石进行定位。使用HM3碎石机(德国慕尼黑多尼尔公司)进行ESWL治疗。
ESWL治疗后,17.1%的患者结石完全清除。另有57.1%的患者需要进一步内镜取石以实现结石完全清除,20.0%的患者出院时仍有小的残留结石碎片。其余2例患者(5.7%)需要手术干预。35例患者中的34例(97.1%)接受了平均27±11个月的随访。5例患者(14.3%)在ESWL后平均13.8±5.7个月出现结石复发。
ESWL是老年高危患者内镜治疗困难胆总管结石的一种有用且安全的辅助方法。一年后的结石复发率约为14%。所有复发结石均可通过内镜治疗。