Teale P, Delmore J, Simon J, Reite M
Department of Psychiatry, University of Colorado Health Sciences Center, Denver 80262.
Brain Res Bull. 1994;33(5):615-20. doi: 10.1016/0361-9230(94)90087-6.
We recorded magnetic auditory evoked fields from the left hemisphere of a 2-year-old 3.4 kg Macaca nemestrina monkey. Three separate components were isolated from each of three data sets with latencies of approximately 22 ms, 46 ms, and 130 ms after stimulus onset. The 46 ms latency component had clear extrema values and was selected for localization. Field values from 21 recording points were used to estimate the 3-D source location of the 46 ms latency component, termed the M46. High resolution MR images of the brain provided information for correlation of neuroanatomic structure with source location. The neuroanatomic source was found to lie in the superior aspect of the temporal lobes bilaterally. We believe the M46 is the macaque analog of the human M100. Recording of auditory evoked fields in nonhuman primates offers a valuable animal model for studying neurophysiology of human magnetoencephalographically (MEG) determined auditory sources.
我们记录了一只体重3.4千克、2岁的豚尾猕猴左半球的磁听觉诱发电场。从三个数据集中的每一个分离出三个单独的成分，刺激开始后潜伏期分别约为22毫秒、46毫秒和130毫秒。46毫秒潜伏期成分有明显的极值，被选用于定位。来自21个记录点的场值用于估计46毫秒潜伏期成分（称为M46）的三维源位置。大脑的高分辨率磁共振图像为神经解剖结构与源位置的相关性提供了信息。发现神经解剖源位于双侧颞叶的上侧。我们认为M46是人类M100在猕猴中的类似物。在非人类灵长类动物中记录听觉诱发电场为研究人类脑磁图（MEG）确定的听觉源的神经生理学提供了一个有价值的动物模型。
