Papanicolaou A C, Baumann S, Rogers R L, Saydjari C, Amparo E G, Eisenberg H M
Division of Neurosurgery, University of Texas Medical Branch, Galveston 77550.
Arch Neurol. 1990 Jan;47(1):33-7. doi: 10.1001/archneur.1990.00530010041016.
Magnetoencephalography offers the possibility of localizing accurately and noninvasively the source of intracranial currents associated with normal and abnormal brain activity. The purpose of this study was to assess the validity and across-subject reliability of localization of cortical sources responding to ipsilateral and contralateral auditory stimulation. Magnetic evoked fields to both stimulation conditions were measured in eight consecutive normal subjects, and the cortical sources of these fields were estimated on the basis of these measurements. Subsequent projection of the source location coordinates onto magnetic resonance images showed that in all subjects the sources were accurately estimated to fall in the vicinity of the auditory cortex and that two separate sources may account for the response to ipsilateral and contralateral stimulation.
脑磁图提供了准确且无创地定位与正常和异常脑活动相关的颅内电流源的可能性。本研究的目的是评估对同侧和对侧听觉刺激作出反应的皮质源定位的有效性和受试者间可靠性。在八名连续的正常受试者中测量了两种刺激条件下的磁诱发电场，并根据这些测量估计了这些电场的皮质源。随后将源位置坐标投影到磁共振图像上显示，在所有受试者中，源被准确估计位于听觉皮层附近，并且两个独立的源可能解释了对同侧和对侧刺激的反应。
