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低密度脂蛋白去除术对血管成形术后再狭窄的影响。

Effects of LDL apheresis on restenosis after angioplasty.

作者信息

Kanemitsu S, Tekekoshi N, Murakami E

机构信息

Department of Cardiology, Kanazawa Medical University, Ishikawa, Japan.

出版信息

Chem Phys Lipids. 1994 Jan;67-68:339-43. doi: 10.1016/0009-3084(94)90155-4.

DOI:10.1016/0009-3084(94)90155-4
PMID:8187232
Abstract

We performed long-term maintenance LDL apheresis therapy on patients with hypercholesterolemia after undergoing PTCA, and investigated the therapeutic effects of reducing serum cholesterol, LDL-cholesterol and Lp(a). LDL apheresis significantly reduced serum lipids and was an efficacious therapy in the prevention of recurrent stenosis after PTCA.

摘要

我们对接受经皮冠状动脉腔内血管成形术(PTCA)后的高胆固醇血症患者进行了长期维持性低密度脂蛋白(LDL)单采治疗,并研究了其降低血清胆固醇、低密度脂蛋白胆固醇和脂蛋白(a)的治疗效果。LDL单采显著降低了血脂,是预防PTCA术后再狭窄的有效治疗方法。

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1
Effects of LDL apheresis on restenosis after angioplasty.低密度脂蛋白去除术对血管成形术后再狭窄的影响。
Chem Phys Lipids. 1994 Jan;67-68:339-43. doi: 10.1016/0009-3084(94)90155-4.
2
Effectiveness of LDL-apheresis in preventing restenosis after percutaneous transluminal coronary angioplasty (PTCA): LDL-apheresis angioplasty restenosis trial (L-ART).低密度脂蛋白去除术预防经皮腔内冠状动脉成形术(PTCA)后再狭窄的有效性:低密度脂蛋白去除术血管成形术再狭窄试验(L-ART)
Chem Phys Lipids. 1994 Jan;67-68:399-403. doi: 10.1016/0009-3084(94)90162-7.
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Short-term and long-term effects of low-density lipoprotein (LDL) apheresis on restenosis after percutaneous transluminal coronary angioplasty (PTCA): is lowering Lp(a) by LDL apheresis effective on restenosis after PTCA?
Ther Apher. 1998 Feb;2(1):65-70. doi: 10.1111/j.1744-9987.1998.tb00075.x.
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Prevention of restenosis after coronary angioplasty with low-density lipoprotein apheresis.
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LDL apheresis in a homozygous familial hypercholesterolemic child aged 4.5.一名4.5岁纯合子家族性高胆固醇血症儿童的低密度脂蛋白单采术
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Can aggressive lipid lowering using low-density lipoprotein apheresis prevent restenosis after percutaneous transluminal coronary angioplasty in patients with normocholesterolemia?
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Low-density lipoprotein apheresis as long-term treatment for children with homozygous familial hypercholesterolemia.低密度脂蛋白单采术作为纯合子家族性高胆固醇血症患儿的长期治疗方法。
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Long-term effect of low-density lipoprotein apheresis on plasma lipoproteins and coronary heart disease in native vessels and coronary bypass in severe heterozygous familial hypercholesterolemia.低密度脂蛋白分离术对严重杂合子家族性高胆固醇血症患者天然血管及冠状动脉搭桥术后血浆脂蛋白和冠心病的长期影响。
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Short- and long-term effects of LDL-apheresis on lipoprotein (a) serum levels.
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引用本文的文献

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Plasmin activation system in restenosis: role in pathogenesis and clinical prediction?再狭窄中的纤溶酶激活系统:在发病机制及临床预测中的作用?
J Thromb Thrombolysis. 1999 Jun;7(3):277-85. doi: 10.1023/a:1008983110941.
2
A variant of human paraoxonase/arylesterase (HUMPONA) gene is a risk factor for coronary artery disease.人类对氧磷酶/芳基酯酶(HUMPONA)基因的一种变体是冠状动脉疾病的一个风险因素。
J Clin Invest. 1995 Dec;96(6):3005-8. doi: 10.1172/JCI118373.