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心脏手术感染预防的免疫学方面(作者译)

[Immunologic aspects to the prevention of infection cardiac surgery (author's transl)].

作者信息

Gierhake F W, Johannsen R, Meyer-Hoepfel W, Meyer-Hoepfel I, Herget H F, Stöcker R, Carlsson A B, L'Allemand H, Hehrlein F W

出版信息

Thoraxchir Vask Chir. 1975 Aug;23(4):417-22. doi: 10.1055/s-0028-1096997.

Abstract
  1. The humoral immunosystem is impaired in those cases of catabolic metabolism in which quantitative and qualitative insufficient alimentation is expected after operation. 2. We showed that after cardiac surgery with extracorporal circulation as well as after other operations a reasonably balanced parenteral nutrition composed of carbohydrates and amino acids could considerably inhibit the changes in the humoral immunity, which is a valuable contribution to the prevention of infection. 3. In our experiments on transformation of lymphocytes after mitogenic stimulation, the depressive effects of operation on the cellular immunity were found to be etiologically more complex than was previously assumed in publications.
摘要
  1. 在那些分解代谢的病例中,体液免疫系统会受损,此类病例预计术后营养供应在数量和质量上均不足。2. 我们发现,在体外循环心脏手术后以及其他手术后,由碳水化合物和氨基酸组成的合理均衡的肠外营养能够显著抑制体液免疫的变化,这对预防感染有重要作用。3. 在我们关于有丝分裂原刺激后淋巴细胞转化的实验中,发现手术对细胞免疫的抑制作用在病因学上比以往出版物中所认为的更为复杂。

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Depression of host-defence mechanisms following cardiac surgery.
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