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手术的免疫抑制作用及其可能的局限性(作者译)

[Immunosuppressive effects of operations and their possible limitation (author's transl)].

作者信息

Gierhake F W, Johannsen R, Stöcker R, Rickmeyer L, Ebert K P, Meyer-Hoepfel W, Meyer-Hoepfel I

出版信息

Immun Infekt. 1975 Jul;3(3):116-24.

PMID:810408
Abstract
  1. The humoral immunosystem is impaired in those cases of catabolic metabolism in which quantitative and qualitative insufficient alimentation is expected after operation. 2. After cholecystectomies as well as after cardiac surgery with extracorporal circulation a reasonably balanced parenteral nutrition composed of carbohydrates and amino acids would considerably inhibit the changes in the humoral immunity, which is a valuable contribution to the prevention of infection. 3. In our experiments on transformation of lymphocytes after mitogenic stimulation, the depressive effects of operation of the cellular immunity were found to be etiologically more complex than was previously assumed in publications.
摘要
  1. 在那些分解代谢的病例中,体液免疫系统会受损,因为预计术后营养供给在数量和质量上均不足。2. 在胆囊切除术后以及体外循环心脏手术后,由碳水化合物和氨基酸组成的合理均衡的肠外营养会在很大程度上抑制体液免疫的变化,这对预防感染有重要作用。3. 在我们关于有丝分裂原刺激后淋巴细胞转化的实验中,发现手术对细胞免疫的抑制作用在病因学上比以前出版物中所认为的更为复杂。

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