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[对猴空泡病毒(LPV)诱导的猴子病理过程的进一步研究]

[Further study of the pathological process induced in monkeys by LPV oncornavirus].

作者信息

Andzhaparidze O G, Stepanova L G, Rozina E E, Prianichnikova L V

出版信息

Vopr Virusol. 1975 Nov-Dec(6):666-72.

PMID:818816
Abstract

Experiments were performed on pathogenicity of LPV oncornavirus and Mason-Pfizer-like virus for monkeys Macaca mulatta. The mixture of culture fluid and cell homogenate ultrafiltrates of virus-producing T-9 cell line was used as a source of LPV virus. The same materials derived from HEp-2 continuous cell line served as a source of Mason-Pfizer-like virus. As a control monkeys were inoculated with ultrafiltrates from human diploid cells. The clinical and pathomorphological analysis of experimental results leads to the conclusion, that only LPV virus induced different forms of haemacytoblastosis in monkeys that confirms our previous observations.

摘要

对劳氏肉瘤病毒(LPV)致瘤病毒和梅森 - 辉瑞样病毒对恒河猴的致病性进行了实验。产生病毒的T - 9细胞系的培养液和细胞匀浆超滤液混合物用作LPV病毒的来源。来自人胚肺二倍体细胞系(HEp - 2)的相同材料用作梅森 - 辉瑞样病毒的来源。作为对照,给猴子接种人二倍体细胞的超滤液。对实验结果的临床和病理形态学分析得出结论,只有LPV病毒能在猴子中诱导出不同形式的成血细胞增多症,这证实了我们之前的观察结果。

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