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Localization of the gene encoding the alpha 2/delta subunit (CACNL2A) of the human skeletal muscle voltage-dependent Ca2+ channel to chromosome 7q21-q22 by somatic cell hybrid analysis.

作者信息

Powers P A, Scherer S W, Tsui L C, Gregg R G, Hogan K

机构信息

William S. Middleton Memorial Veterans Hospital, Madison, Wisconsin.

出版信息

Genomics. 1994 Jan 1;19(1):192-3. doi: 10.1006/geno.1994.1044.

DOI:10.1006/geno.1994.1044
PMID:8188232
Abstract
摘要

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Identification of three novel Ca(2+) channel gamma subunit genes reveals molecular diversification by tandem and chromosome duplication.三个新的钙离子通道γ亚基基因的鉴定揭示了通过串联和染色体复制实现的分子多样化。
Genome Res. 1999 Dec;9(12):1204-13. doi: 10.1101/gr.9.12.1204.
3
Malignant-hyperthermia susceptibility is associated with a mutation of the alpha 1-subunit of the human dihydropyridine-sensitive L-type voltage-dependent calcium-channel receptor in skeletal muscle.
恶性高热易感性与人类骨骼肌中对二氢吡啶敏感的L型电压依赖性钙通道受体α1亚基的突变有关。
Am J Hum Genet. 1997 Jun;60(6):1316-25. doi: 10.1086/515454.