血清类黏蛋白（ORM）类型与银屑病之间的关联。
Association between orosomucoid (ORM) types and psoriasis.
作者信息
Fan C, Lidén S
机构信息
Department of Medical Genetics, University of Umeå, Sweden.
出版信息
Hum Hered. 1994 Mar-Apr;44(2):72-6. doi: 10.1159/000154194.
PMID:8188313
Abstract
Orosomucoid (ORM) types were studied by isoelectric focusing and immunoblotting in 175 psoriatic patients and 2,217 blood donor controls from the county of Västerbotten in northern Sweden. There was a significant difference between patients and controls with respect to the distribution of ORM types (p = 4 x 10(-4)). The ORM1 1 type showed an increased frequency among the psoriatic patients (p = 1 x 10(-4) with a relative risk of 1.82 (95% CI:1.34-2.48).
摘要
通过等电聚焦和免疫印迹法，对瑞典北部韦斯特博滕县的175名银屑病患者和2217名献血者对照进行了类粘蛋白（ORM）类型研究。患者和对照在ORM类型分布方面存在显著差异（p = 4×10⁻⁴）。ORM1 1型在银屑病患者中的频率增加（p = 1×10⁻⁴），相对风险为1.82（95%可信区间：1.34 - 2.48）。
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