Wong O, Foliart D E
Applied Health Sciences, San Mateo, CA 94401.
J Environ Pathol Toxicol Oncol. 1993 Oct-Dec;12(4):171-83.
Certain Louisiana cancer rates are higher than the national averages. This review evaluates the existing epidemiologic literature pertaining to risk factors for cancer in Louisiana. Population-based case-control studies have identified smoking as the most important contributor to lung cancer in Louisiana. Nutritional factors have been found to impart a modest increase in lung, pancreas, and stomach cancer risk. Occupational epidemiologic studies have revealed exposure to asbestos in the cement, shipbuilding, and related industries as a significant risk factor for mesothelioma and lung cancer. Sugarcane farming has been found to increase the risk of lung cancer among sugarcane farmers who smoke, and the risk of mesothelioma among sugarcane farmers in general. Occupations with exposure to microwave and radio frequency electromagnetic radiation have been associated with an increased risk of brain cancer. An increased risk of laryngeal cancer has been observed among workers exposed to sulfuric acid at a Baton Rouge isopropyl alcohol plant. Except for the laryngeal cancer finding, data from occupational cohort studies of refinery/chemical workers revealed no significant excess in cancer of all sites, cancer of the lung, or any other cancer. Relevant epidemiologic data also revealed no increased cancer risk associated with potential exposures to industrial emissions among residents in communities adjacent to petrochemical facilities.
路易斯安那州的某些癌症发病率高于全国平均水平。本综述评估了与路易斯安那州癌症风险因素相关的现有流行病学文献。基于人群的病例对照研究已确定吸烟是路易斯安那州肺癌的最重要促成因素。已发现营养因素会适度增加患肺癌、胰腺癌和胃癌的风险。职业流行病学研究表明,在水泥、造船及相关行业接触石棉是间皮瘤和肺癌的重要风险因素。已发现甘蔗种植会增加吸烟的甘蔗种植者患肺癌的风险,以及一般甘蔗种植者患间皮瘤的风险。接触微波和射频电磁辐射的职业与患脑癌风险增加有关。在巴吞鲁日一家异丙醇工厂接触硫酸的工人中,观察到患喉癌的风险增加。除了喉癌这一发现外,炼油厂/化工工人职业队列研究的数据显示,所有部位的癌症、肺癌或任何其他癌症均无显著超额发病情况。相关流行病学数据还显示,石化设施附近社区居民潜在接触工业排放物与癌症风险增加无关。