Friedrich T D, Laffin J, Lehman J M
Department of Microbiology, Immunology and Molecular Genetics, Albany Medical College, New York 12208.
J Virol. 1994 Jun;68(6):4028-30. doi: 10.1128/JVI.68.6.4028-4030.1994.
Previous experiments with the simian virus 40 mutant tsA357R-K (tsA30) demonstrated a T-antigen function that is required for production of cells with a greater-than-G2-phase DNA content. In this study, temperature shift experiments indicated that the temperature-sensitive function of tsA357R-K, which is necessary for entry into the greater-than-G2 phase, is not required in G1 or S but must be supplied in the G2 phase.