Okuhata Y, Xia T, Urahashi S, Arimizu N
Department of Radiology, Nihon University School of Medicine.
Nihon Igaku Hoshasen Gakkai Zasshi. 1994 Apr 25;54(5):410-2.
First clinical trial of MR lymphography is described. The subjects were two normal volunteers. The contrast agent was cideferron, which was an iron colloid. We obtained MR images of the inguinal lymph nodes before and after subcutaneous injection of the agent in the dorsal feet. As a result, the signal intensities on T2 weighted images remarkably decreased at two hours after injection and kept low until three months after. Although pigmentation around the injection site was observed, it was gradually fading within six months. In conclusion, MR lymphography with cideferron can be applied clinically.
描述了首例磁共振淋巴造影临床试验。受试者为两名正常志愿者。造影剂为西铁多胺,一种铁胶体。我们在背侧足部皮下注射该造影剂前后获取了腹股沟淋巴结的磁共振图像。结果,注射后两小时T2加权图像上的信号强度显著降低,并在三个月内一直保持较低水平。尽管在注射部位周围观察到色素沉着,但在六个月内逐渐消退。总之,使用西铁多胺的磁共振淋巴造影可应用于临床。