Matuszczyk J V, Larsson K
Department of Psychology, University of Göteborg, Sweden.
Physiol Behav. 1994 Mar;55(3):527-31. doi: 10.1016/0031-9384(94)90112-0.
The aim of this study was to investigate whether heterosexual experience influences the male's partner preference and the role of gonadal hormones, including several androgens and estradiol, on female-oriented behavior. In the first experiment, the animals were exposed to a four-stimuli test situation including a sexually active male, a castrated male, an estrous female, and an ovariectomized (ovx) female. Castrated naive and experienced male rats were implanted with either testosterone (T), estradiol (E2), or an empty tubing (blank) and compared to intact naive and experienced male rats. None of the naive animals, whether castrated or intact, showed a consistent preference for any of the four stimuli. Whereas when sexually experienced, only intact and T-treated males showed a female-oriented preference. In the second experiment, the animals were allowed to choose between an active male and an estrous female. Castrated naive male rats were implanted with either T, E2, or DHT, or injected daily SC with the synthetic nonaromatizable androgen, methyltrienelone (R 1881). Two groups of intact males, one consisting of experienced and the other of naive animals, were also included in this experiment. The experienced intact males showed a significant preference for the estrous female, while the intact naive males showed no preference for either of the two stimuli. After the animals had gained heterosexual experience, intact and androgen-treated males showed a significant preference for the female. Neither the administration of R 1881 nor E2 promoted a female-oriented behavior.(ABSTRACT TRUNCATED AT 250 WORDS)
本研究的目的是调查异性恋经历是否会影响雄性的配偶偏好，以及性腺激素（包括几种雄激素和雌二醇）在以雌性为导向行为中的作用。在第一个实验中，将动物置于包含性活跃雄性、去势雄性、发情雌性和卵巢切除（ovx）雌性的四刺激测试情境中。将去势的未经历过和经历过异性接触的雄性大鼠植入睾酮（T）、雌二醇（E2）或空管（空白对照），并与完整的未经历过和经历过异性接触的雄性大鼠进行比较。无论是去势还是完整的未经历过异性接触的动物，均未对这四种刺激中的任何一种表现出一致的偏好。然而，当有过性经历时，只有完整的和接受T处理的雄性表现出以雌性为导向的偏好。在第二个实验中，让动物在性活跃雄性和发情雌性之间进行选择。将去势的未经历过异性接触的雄性大鼠植入T、E2或双氢睾酮（DHT），或每天皮下注射合成的不可芳香化雄激素甲基三烯olone（R1881）。该实验还包括两组完整的雄性大鼠，一组由经历过异性接触的动物组成，另一组由未经历过异性接触的动物组成。经历过异性接触的完整雄性大鼠对发情雌性表现出显著偏好，而完整的未经历过异性接触的雄性大鼠对这两种刺激均无偏好。在动物获得异性恋经历后，完整的和接受雄激素处理的雄性对雌性表现出显著偏好。给予R1881和E2均未促进以雌性为导向的行为。（摘要截选至250字）
