Fernández-Guasti A, Omaña-Zapata I, Luján M, Condés-Lara M
Departamento de Farmacología, Cinvestav, UNAM, México City, México.
Physiol Behav. 1994 Mar;55(3):577-81. doi: 10.1016/0031-9384(94)90119-8.
The action of the hyperalgesia produced by the loose ligature of the sciatic nerve on the sexual behavior of two groups of sexually experienced and inexperienced male rats was studied. The putative changes in the behavior induced by this manipulation were attempted to be counteracted by the removal of the anterior frontal cortex. Independently of the sexual experience, the ligature of the sciatic nerve did not modify any parameter of the sexual behavior, except for a slight prolongation of the intromission latency. Surprisingly, the removal of the cortical frontal pole resulted in drastic changes in the sexual behavior of sexually inexperienced male rats such as an increase in the intromission and ejaculation latencies and the postejaculatory interval. These changes were not observed in the sexually experienced group. Interestingly, the sciatic nerve ligature prevented the changes in the copulatory behavior produced by the frontal cortex removal. These results suggest that the hyperalgesia induced by the sciatic nerve ligature was unable to alter the sexual behavior. By contrast, the frontal cortex removal produced important changes in the sexual behavior that depend upon the previous sexual experience. All results are discussed on the bases of the neural control underlying the possible relationships between algesia and male sexual behavior.
研究了坐骨神经松结扎所致痛觉过敏对两组有性经验和无性经验雄性大鼠性行为的影响。试图通过切除前额叶皮质来抵消这种操作引起的行为假定变化。无论性经验如何，坐骨神经结扎除了使插入潜伏期稍有延长外，并未改变性行为的任何参数。令人惊讶的是，切除皮质额极导致无性经验雄性大鼠的性行为发生剧烈变化，如插入和射精潜伏期以及射精后间隔时间增加。在有性经验的组中未观察到这些变化。有趣的是，坐骨神经结扎阻止了切除额叶皮质所产生的交配行为变化。这些结果表明，坐骨神经结扎诱导的痛觉过敏无法改变性行为。相比之下，切除额叶皮质会使性行为发生重要变化，这取决于先前的性经验。所有结果均基于痛觉过敏与雄性性行为之间可能关系的神经控制进行讨论。
