Claro F, Segovia S, Guilamón A, Del Abril A
Departamento de Psicobiología, Universidad Nacional de Educación a Distancia, Ciudad Universitaria, Madrid, Spain.
Brain Res Bull. 1995;36(1):1-10. doi: 10.1016/0361-9230(94)00118-k.
Previous studies have showed that lesions in the bed nucleus of the stria terminalis of experienced male rats impair some parameters of sexual behavior. The aim of this study was to examine the contribution of the medial posterior region of the bed nucleus of the stria terminalis (BSTMP), a sexually dimorphic region of this nucleus that pertains to the vomeronasal system, to the modulation of sexual behavior of the male rat. Small electrolytic bilateral lesions in the BSTMP were made in male heterosexual experienced and inexperienced rats. Sham lesioned animals were also tested as a control of the effects of the general surgical procedures. Behavioral tests were then performed to obtain standard measures of masculine sexual behavior. Our results indicate that the sexually experienced male rats with lesioned BSTMPs showed increases in the number of mounts and the number of intromissions and, consequently, in ejaculation latency. In contrast, the sexually naive male rats showed increases in first mount and intromission latencies and in ejaculation latency, but the latter occurred due to increases in the interintromission intervals. This group also showed low correlations between olfactory investigation of the anogenital area of the female and initiation and maintenance of copulatory behavior. The results suggest that sexual experience obtained in the very artificial conditions of laboratory tests could supply some of the cues provided by the BSTMP in the process of sensorial integration, which we hypothesize modulates the initiation and pacing of copulation. However, sexual experience does not apparently supply any other kinds of cues provided or processed in the BSTMP that are involved in modulating the elicitation of intromissions and ejaculations.
先前的研究表明，有经验的雄性大鼠终纹床核中的损伤会损害性行为的某些参数。本研究的目的是检验终纹床核内侧后部区域（BSTMP），即该核中与犁鼻系统相关的一个性别二态性区域，对雄性大鼠性行为调节的作用。在有性经验和无性经验的雄性异性恋大鼠的BSTMP中进行了双侧小电解损伤。作为一般手术程序影响的对照，也对假损伤动物进行了测试。然后进行行为测试以获得雄性性行为的标准测量值。我们的结果表明，BSTMP损伤的有性经验雄性大鼠的爬跨次数和插入次数增加，射精潜伏期也随之增加。相比之下，性幼稚的雄性大鼠首次爬跨和插入潜伏期以及射精潜伏期增加，但后者是由于插入间隔增加所致。该组在对雌性肛门生殖器区域的嗅觉探究与交配行为的启动和维持之间也显示出低相关性。结果表明，在非常人工的实验室测试条件下获得的性经验可以提供BSTMP在感觉整合过程中提供的一些线索，我们假设这些线索调节交配的启动和节奏。然而，性经验显然不能提供BSTMP中提供或处理的参与调节插入和射精引发的任何其他类型的线索。
