Cressa C, Gozzi G, Tonutti M, Macorig D, Tessa I
Istituto di Radiologia, Università degli Studi, Trieste.
Radiol Med. 1994 Apr;87(4):405-11.
To compare the diagnostic value and the role of plain radiographic magnification and of ultrasonography (US) in breast cancer evaluation, 83 malignant tumors were studied with mammography, plain radiographic magnification and US. Microcalcifications were not included in our study. All tumors subsequently underwent histology or cytology. In our series, the malignant nature of the lesion was unquestionably proved in 53% of cases while a possible malignancy was suspected in 36% and a benign nature was incorrectly suspected in 11% of cases with mammography. The diagnostic value of plain radiographic magnification was compared with that of US; breast patterns, mammographic and clinical findings were considered. As for breast patterns, plain radiographic magnification was more accurate in evaluating fatty breast than both mammography and US, allowing the correct diagnosis of 58% of questionable mammographic findings, vs. 33% of US. On the contrary, US was more accurate in dense breasts, allowing the correct diagnosis of 77.7% of mammographic misdiagnoses vs. 33.3% only of plain radiographic magnification. As far as mammography is concerned, US was more accurate than plain radiographic magnification in the assessment of round masses (71.4% vs. 38.1%, respectively), whereas plain radiographic magnification was more accurate than US in stellate masses (100% vs. 92.7%, respectively). As far as clinical findings are concerned, plain radiographic magnification sensitivity was substantially the same in the assessment of symptomatic and asymptomatic lesions (91.5% vs. 89%, respectively), whereas US sensitivity was higher in symptomatic (97%) than in asymptomatic (69%) lesions. The rate of false-negative US diagnoses (14.4%) was higher than those of mammography and of plain radiographic magnification. Negative US findings must be considered with caution and are not sufficient to settle a radiologic doubt.
为比较乳腺钼靶摄影、普通X线放大摄影及超声检查在乳腺癌评估中的诊断价值和作用,我们对83例恶性肿瘤进行了乳腺钼靶摄影、普通X线放大摄影及超声检查。本研究未纳入微钙化情况。所有肿瘤随后均接受了组织学或细胞学检查。在我们的研究系列中,乳腺钼靶摄影确诊病变为恶性的病例占53%,怀疑可能为恶性的病例占36%,误诊为良性的病例占11%。比较了普通X线放大摄影与超声检查的诊断价值;同时考虑了乳腺类型、乳腺钼靶摄影及临床检查结果。就乳腺类型而言,普通X线放大摄影在评估脂肪型乳腺方面比乳腺钼靶摄影及超声检查更准确,能正确诊断58%的乳腺钼靶可疑发现,而超声检查仅为33%。相反,超声检查在致密型乳腺中更准确,能正确诊断77.7%的乳腺钼靶误诊,而普通X线放大摄影仅为33.3%。就乳腺钼靶摄影而言,超声检查在评估圆形肿块方面比普通X线放大摄影更准确(分别为71.4%和38.1%),而普通X线放大摄影在评估星芒状肿块方面比超声检查更准确(分别为100%和92.7%)。就临床检查结果而言,普通X线放大摄影在评估有症状和无症状病变时的敏感性基本相同(分别为91.5%和89%),而超声检查在有症状病变中的敏感性(97%)高于无症状病变(69%)。超声检查的假阴性诊断率(14.4%)高于乳腺钼靶摄影和普通X线放大摄影。对超声检查阴性结果必须谨慎考虑,其不足以消除放射学怀疑。