van Oord J C, van der Vliet A M, Thyn C J, Mak B, Hoogeboom G J
Department of Diagnostic Radiology, University Hospital, Groningen, The Netherlands.
Rofo. 1991 Jul;155(1):63-6. doi: 10.1055/s-2008-1033220.
Between January 1987 and May 1988 a prospective study was carried out on 232 women with a palpable breast mass. They underwent physical examination, x-ray mammography and ultrasound mammography. The results of each study were interpreted independently by separate observers, and consensus was achieved. From all solid tumours histology was available. Compared to x-ray mammography, ultrasound mammography proved to be significantly (p less than 0.025) more sensitive in diagnosing malignant palpable breast masses (98.7% versus 86.8%). However there was no statistical significant difference in specificity between ultrasound mammography and x-ray mammography. Using ultrasound mammography we classified 9 histological proven malignant tumours as such which were negative on plain x-ray mammography. Despite the good results of ultrasound mammography in diagnosing palpable breast lesions it can never replace x-ray mammography in cases of malignancy, because the results of ultrasound mammography with non-palpable synchronous tumours with or without microcalcifications are poor. In some cases of benign lesions diagnosed with ultrasound mammography no x-ray mammography is necessary.
1987年1月至1988年5月期间,对232名可触及乳腺肿块的女性进行了一项前瞻性研究。她们接受了体格检查、乳腺X线摄影和超声乳腺摄影。每项检查的结果由不同的观察者独立解读,并达成共识。所有实性肿瘤均有组织学检查结果。与乳腺X线摄影相比,超声乳腺摄影在诊断可触及的恶性乳腺肿块方面明显更敏感(p<0.025)(98.7%对86.8%)。然而,超声乳腺摄影和乳腺X线摄影在特异性方面没有统计学显著差异。使用超声乳腺摄影,我们将9例经组织学证实为恶性的肿瘤归类为此类,而这些肿瘤在普通乳腺X线摄影中为阴性。尽管超声乳腺摄影在诊断可触及乳腺病变方面效果良好,但在恶性肿瘤病例中它永远无法取代乳腺X线摄影,因为对于不可触及的同步肿瘤,无论有无微钙化,超声乳腺摄影的结果都很差。在一些经超声乳腺摄影诊断为良性病变的病例中,无需进行乳腺X线摄影。