Rooholamini S A, Tehrani N S, Razavi M K, Au A H, Hansen G C, Ostrzega N, Verma R C
Department of Radiological Sciences, Olive View--UCLA Medical Center, Sylmar 91342.
Radiographics. 1994 Mar;14(2):291-306. doi: 10.1148/radiographics.14.2.8190955.
Although carcinoma of the gallbladder has a low overall prevalence, it is the most common malignant tumor of the biliary tract. Retrospectively, 59 cases of histologically proved gallbladder carcinoma were reviewed. The series consisted of 42 women and 17 men, ranging in age from 35 to 86 years. Clinical manifestations of gallbladder carcinoma include right upper quadrant pain, anorexia, weight loss, and jaundice. Radiologic findings included focal or diffuse thickening of the gallbladder wall (49%), a mass in the gallbladder fossa (37%), and an intraluminal mass (14%). Associated findings were cholelithiasis (64%), biliary duct dilatation (38%), invasion of the adjacent structures (67%), distant metastases other than those of the liver (3%), and porcelain gallbladder (4%). The histologic diagnoses were adenocarcinoma (90%) and squamous cell carcinoma (10%). Differential diagnoses include all conditions in which the gallbladder wall appears thickened. A general awareness of the radiologic features of gallbladder carcinoma enhances preoperative diagnoses.
尽管胆囊癌的总体发病率较低，但它是胆道最常见的恶性肿瘤。回顾性地分析了59例经组织学证实的胆囊癌病例。该系列病例包括42名女性和17名男性，年龄在35至86岁之间。胆囊癌的临床表现包括右上腹疼痛、厌食、体重减轻和黄疸。放射学表现包括胆囊壁局限性或弥漫性增厚（49%）、胆囊窝肿块（37%）和腔内肿块（14%）。相关表现有胆石症（64%）、胆管扩张（38%）、侵犯相邻结构（67%）、非肝脏的远处转移（3%）和瓷胆囊（4%）。组织学诊断为腺癌（90%）和鳞状细胞癌（10%）。鉴别诊断包括所有胆囊壁增厚的情况。对胆囊癌放射学特征的普遍认识有助于提高术前诊断。
