Sakharchuk I I, Gol'denberg G M, Bobrova E V
Lik Sprava. 1993 Feb-Mar(2-3):118-20.
A study is presented of the structure and function of the heart in the diastole in 39 patients during corinfar treatment of essential hypertension. It was established that effective corinfar monotherapy of patients with moderate essential hypertension was associated with arteriolo- and venodilating effect of the drug with prevalence of the preloading effect. Changes of the intracardiac hemodynamics resulted in changes of the left ventricular systole phase structure, namely, its transformation in the direction of myocardial hypodynamia.
对39例原发性高血压患者在进行可乐定治疗时心脏舒张期的结构和功能进行了一项研究。结果表明,可乐定对中度原发性高血压患者的单一有效治疗与该药物的小动脉和静脉舒张作用有关,且前负荷作用占优势。心内血流动力学的变化导致左心室收缩期相结构发生变化,即向心肌动力不足方向转变。