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吸入低氧和高氧分数对异氟烷麻醉鸭通气的影响。

Effects of low and high fractions of inspired oxygen on ventilation in ducks anesthetized with isoflurane.

作者信息

Seaman G C, Ludders J W, Erb H N, Gleed R D

机构信息

Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853.

出版信息

Am J Vet Res. 1994 Mar;55(3):395-8.

PMID:8192265
Abstract

High fractions of inspired oxygen are commonly used during general anesthesia in birds. Observations in ducks anesthetized with halothane or pentobarbital indicated that high fractions of inspired oxygen depress ventilation. The purpose of this study was to test the hypothesis that ducks hypoventilate when breathing high fractions of inspired oxygen, compared with the same ducks breathing low fractions of inspired oxygen. Respiratory variables were recorded in 7 ducks anesthetized with 1.4% isoflurane in oxygen. Four concentrations of oxygen (21, 40, 70, and > 90%) were used for each duck. Respiratory rate decreased as the fraction of inspired oxygen increased, but not significantly. There was a significant decrease in tidal volume as PaCO2 increased. Hyperoxia was observed to contribute to hypoventilation in ducks anesthetized with isoflurane in oxygen.

摘要

鸟类全身麻醉期间通常会使用高浓度的吸入氧。对用氟烷或戊巴比妥麻醉的鸭子的观察表明,高浓度的吸入氧会抑制通气。本研究的目的是检验这一假设:与吸入低浓度氧的同一只鸭子相比,鸭子在吸入高浓度氧时会出现通气不足。记录了7只用1.4%异氟烷和氧气麻醉的鸭子的呼吸变量。每只鸭子使用四种氧浓度(21%、40%、70%和>90%)。随着吸入氧浓度的增加,呼吸频率下降,但不显著。随着动脉血二氧化碳分压(PaCO2)升高,潮气量显著下降。观察到高氧血症会导致用异氟烷和氧气麻醉的鸭子通气不足。

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