Synthesis and in vitro cytotoxic activity of new n-diazoacetylglycine derivatives.
作者信息
Loggia R D, Furlani A, Savastano F, Scarcia V
出版信息
Experientia. 1976 May 15;32(5):636-8. doi: 10.1007/BF01990207.
PMID:819289
Abstract
The syntheses of various N-diazoacetylglycine derivatives are described. The results of an in vitro screening carried out on KB cells for cytotoxic activity are reported. The most active compounds are DGE, DGiBA and DGHA. A possible relationship between the activity and the liposolubility of these compounds is discussed.
摘要
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