Lachiewicz A M, Spiridigliozzi G A, Gullion C M, Ransford S N, Rao K
Duke University Medical Center.
Am J Ment Retard. 1994 Mar;98(5):567-79.
To determine whether aberrant behaviors described in boys with fragile X syndrome distinguish them from other boys with developmental disabilities, we asked the primary caregivers of 55 boys with fragile X and 57 matched controls to complete five behavioral questionnaires. Twenty-one items distinguished the groups. Principal components analysis (PCA) yielded five behavioral clusters: abnormal language, tactile defensiveness, poor self-control, poor eye contact/shyness, and hand flapping. Boys with fragile X were found times more likely to have both tactile defensiveness and abnormal language. The presence of these abnormal behaviors in boys with developmental delays warrants further assessment for fragile X.
为了确定脆性X综合征男孩所表现出的异常行为是否能将他们与其他发育障碍男孩区分开来，我们让55名脆性X综合征男孩和57名匹配的对照组男孩的主要照顾者完成了五份行为问卷。有21个项目区分了这两组。主成分分析（PCA）产生了五个行为集群：语言异常、触觉防御、自控力差、眼神接触不良/害羞以及拍手。结果发现，脆性X综合征男孩出现触觉防御和语言异常的可能性要高出数倍。发育迟缓男孩中出现这些异常行为，值得对脆性X综合征进行进一步评估。
