Taïeb A, Touati L, Cony M, Léauté-Labrèze C, Mortureux P, Renaud P, Boineau D, Maleville J
Pediatric Dermatology Unit, Pellegrin Childrens Hospital, Bordeaux, France.
Dermatology. 1994;188(4):276-81. doi: 10.1159/000247165.
Over 20 months, we have treated 74 patients (59 children less than 12 years of age) with port-wine stains (PWS) using a 585-nm flashlamp-pulsed dye laser (SPTL-1, Candela Corp., Wayland, Mass., USA) after topical anesthesia with Emla cream. A 5-point reference color scale was used to evaluate the results. 45 patients had at least one treatment on the entire surface of the lesion. A mean of 88 impacts per session was delivered. There was a significant decrease in color in around two thirds of the cases after one complete treatment with a gradual tendency to improvement after subsequent treatments. Younger age at the beginning of treatment was not found to be predictive of a better outcome after the first treatment. In around one third of the cases, positive test site treatment was not correlated with significant improvement after one treatment. Lesions situated on the limbs were less responsive than those on the head and neck. Except for problems due to absence of general anesthesia in young children enduring repeated stressful and sometimes painful procedures, the overall impression is that early treatment of PWS is possible with very limited risks of scarring using this technique.
在20多个月的时间里，我们使用585纳米闪光灯泵浦染料激光（美国马萨诸塞州韦兰市坎德拉公司的SPTL-1），在使用复方利多卡因乳膏进行局部麻醉后，对74例患有葡萄酒色斑（PWS）的患者（59例年龄小于12岁的儿童）进行了治疗。使用5分参考色标评估结果。45例患者对病变的整个表面至少进行了一次治疗。每次治疗平均施加88次脉冲。在一次完整治疗后，约三分之二的病例颜色有显著减轻，后续治疗后有逐渐改善的趋势。未发现治疗开始时年龄较小可预测首次治疗后有更好的效果。在约三分之一的病例中，阳性试验部位治疗与一次治疗后的显著改善无关。位于四肢的病变比头颈部的病变反应性更低。除了因幼儿缺乏全身麻醉而在忍受反复的压力性且有时痛苦的操作过程中出现的问题外，总体印象是使用该技术早期治疗葡萄酒色斑是可行的，且瘢痕形成风险非常有限。
