苏丹儿童急性下呼吸道感染的衣原体病因

Chlamydial etiology of acute lower respiratory tract infections in children in the Sudan.

作者信息

Herrmann B, Salih M A, Yousif B E, Abdelwahab O, Mårdh P A

机构信息

Institute of Clinical Bacteriology, University of Uppsala, Sweden.

出版信息

Acta Paediatr. 1994 Feb;83(2):169-72. doi: 10.1111/j.1651-2227.1994.tb13044.x.

DOI:10.1111/j.1651-2227.1994.tb13044.x

PMID:8193496

Abstract

The role of Chlamydia pneumoniae in 110 Sudanese children with signs of acute lower respiratory tract infections (ALRI) was investigated. Four (3.6%) had evidence of C. pneumoniae infection, of whom 3 were culture-positive, while 1 had an antibody response suggesting a recent infection. IgG antibodies at a titer of > or = 1:32 to C. pneumoniae, Chlamydia psittaci and Chlamydia trachomatis were detected in 27 (24.5%), 27 (24.5%) and 7 (6.4%) of the 110 ALRI cases, respectively. C. pneumoniae, C. trachomatis or C. psittaci were not detected in nasopharyngeal secretions from any of 110 patients when fluorescence-labeled specific monoclonal antibodies were used. In a seroepidemiological survey, 318 healthy Sudanese persons aged between 1 month and 67 years were studied for C. pneumoniae antibodies.

摘要

对110名有急性下呼吸道感染（ALRI）体征的苏丹儿童中肺炎衣原体的作用进行了调查。4名（3.6%）有肺炎衣原体感染的证据，其中3名培养阳性，而1名有提示近期感染的抗体反应。在110例ALRI病例中，分别有27例（24.5%）、27例（24.5%）和7例（6.4%）检测到肺炎衣原体、鹦鹉热衣原体和沙眼衣原体的IgG抗体滴度≥1:32。当使用荧光标记的特异性单克隆抗体时，在110例患者的任何鼻咽分泌物中均未检测到肺炎衣原体、沙眼衣原体或鹦鹉热衣原体。在一项血清流行病学调查中，对318名年龄在1个月至67岁之间的健康苏丹人进行了肺炎衣原体抗体研究。