Nobes C, Hall A
MRC Laboratory for Molecular Cell Biology, University College London, UK.
Curr Opin Genet Dev. 1994 Feb;4(1):77-81. doi: 10.1016/0959-437x(94)90094-9.
During the past year, the small GTP-binding proteins Rho and Rac have each been shown to regulate a signal transduction pathway linking growth factor receptors to distinct changes in the actin cytoskeleton. A number of regulatory molecules for Rho-like proteins have been identified and some of these may cross-talk with the Ras signalling pathway.
在过去的一年里，小GTP结合蛋白Rho和Rac已分别被证明可调节一条信号转导通路，该通路将生长因子受体与肌动蛋白细胞骨架的不同变化联系起来。已鉴定出许多Rho样蛋白的调节分子，其中一些可能与Ras信号通路相互作用。
