Nguyen N X, Korth M, Wisse M, Jünemann A
DFG-Klinische Forschergruppe (NA 55/6-1), Universität Erlangen-Nürnberg.
Klin Monbl Augenheilkd. 1994 Mar;204(3):149-54. doi: 10.1055/s-2008-1035512.
The Color Vision Meter 712 (CVM) is a new automatic computerized anomaloscope relying on both the Rayleigh and the Moreland equation. In the present study the diagnostic value of Color Vision Meter was examined in glaucoma for the first time and was compared with the Farnsworth 100 hue test.
33 normals, 15 patients with ocular hypertension (OHT) and a heterogenic group of 31 glaucoma patients were tested with the Nagel anomaloscope, the Color Vision Meter 712 and the Farnsworth 100 hue test. The following determinations were made in all subjects: 1. Anomalous quotient of the Rayleigh equation of the Nagel anomaloscope and of the Color Vision Meter, 2. Mean tritan score of 100 hue test, 3. The matching range, mid matching point, and anomalous quotient of the Moreland equation with the Color Vision Meter.
While in the OHT group only the matching range of the Moreland equation was enlarged, all three variables (matching range, mid matching point and anomalous quotient) of the Moreland equation were significantly changed in the glaucoma group. The mean tritan score of the 100 hue test showed in the OHT group only a slight difference compared to normals, and in the glaucoma group a low significance and a low sensitivity. The matching range of the Moreland equation seems to be most useful with a sensitivity of 87.1% and a specificity of 93.6%.
Our results show that the new anomaloscope Color Vision Meter 712 should be considered as a quick screening test for the examination of blue-color vision disturbances in glaucoma because of its higher sensitivity, its easier use for examiner and patients, and its shortened examination time (5 min per equation).
712型色觉仪（CVM）是一种新型的自动计算机化色盲检查仪，它同时依赖瑞利方程和莫兰德方程。在本研究中，首次对色觉仪在青光眼诊断中的价值进行了检测，并与 Farnsworth 100色调试验进行了比较。
对33名正常人、15名高眼压症（OHT）患者以及31名不同类型的青光眼患者进行了 Nagel 色盲检查仪、712型色觉仪和 Farnsworth 100色调试验检测。对所有受试者进行了以下测定：1. Nagel 色盲检查仪和色觉仪瑞利方程的异常商；2. 100色调试验的平均蓝色混淆评分；3. 色觉仪莫兰德方程的匹配范围、中间匹配点和异常商。
在高眼压症组中，只有莫兰德方程的匹配范围扩大，而在青光眼组中，莫兰德方程的所有三个变量（匹配范围、中间匹配点和异常商）均有显著变化。100色调试验的平均蓝色混淆评分在高眼压症组与正常人相比仅有轻微差异，在青光眼组中具有较低的显著性和敏感性。莫兰德方程的匹配范围似乎最有用，其敏感性为87.1%，特异性为93.6%。
我们的结果表明，新型色盲检查仪712型色觉仪应被视为一种快速筛查试验，用于检查青光眼患者的蓝色色觉障碍，因为它具有更高的敏感性、对检查者和患者使用更方便以及检查时间缩短（每个方程5分钟）的优点。
