Schäfers H J, Schäfer C M, Zink C, Haverich A, Borst H G
Department of Radiology, Hannover Medical School, Germany.
J Thorac Cardiovasc Surg. 1994 Jun;107(6):1476-80.
The treatment of dehiscence or stenosis of the bronchus after lung transplantation has to date consisted of endobronchial stenting or balloon dilation. Operative intervention has been limited to retransplantation with all its limitations. In our series of 121 anastomoses at risk, severe bronchial stenosis occurred in 11 (9%). In five instances the airway complications were treated surgically: two patients underwent retransplantation, one patient had a bilobectomy, and two required sleeve resection of the stenotic segment. All these procedures successfully removed the stenosis. This experience demonstrates that options other than bronchial anastomotic stenting and dilation may be successfully used to overcome posttransplantation anastomotic complications. Conventional resections may result in superior long-term graft function compared with retransplantation, avoiding the immunologically adverse effects of the latter procedure.
迄今为止,肺移植术后支气管裂开或狭窄的治疗方法包括支气管内支架置入或球囊扩张。手术干预仅限于再次移植,且存在诸多局限性。在我们的121例有风险的吻合术中,11例(9%)发生了严重支气管狭窄。有5例气道并发症接受了手术治疗:2例患者接受了再次移植,1例患者进行了双叶切除术,2例患者需要对狭窄段进行袖状切除术。所有这些手术均成功解除了狭窄。这一经验表明,除支气管吻合口支架置入和扩张外,其他方法也可成功用于克服移植后吻合口并发症。与再次移植相比,传统切除术可能会带来更好的长期移植功能,避免了后者手术的免疫不良反应。