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新泽西州泽西城一家医院的耐多药结核病——1990 - 1992年

Multidrug-resistant tuberculosis in a hospital--Jersey City, New Jersey, 1990-1992.

出版信息

MMWR Morb Mortal Wkly Rep. 1994 Jun 10;43(22):417-9.

PMID:8196587
Abstract

Since 1986 (the first full year following implementation of the revised tuberculosis [TB] surveillance case definition), the reported rate of TB per 100,000 persons in New Jersey increased from 9.5 cases to 12.6 cases in 1992. Of the 984 cases reported to CDC from New Jersey in 1992, 108 (11.0%) were reported from Jersey City (1990 population: 230,300)--the city ranked second in number of TB cases reported and fourth in rate of TB (46.9 per 100,000) in the state. In addition, in 1992, the rate of multidrug-resistant TB (MDR-TB) (i.e., Mycobacterium tuberculosis isolates resistant to at least isoniazid [INH] and rifampin [RIF]) among TB patients in New Jersey was 5%; the rate in Jersey City was 13%. To characterize the epidemiologic features of persons with drug-resistant TB, the New Jersey Department of Health and the Infectious Diseases Division of the Jersey City Medical Center conducted a study among patients treated at that hospital during 1990-1992. This report presents the findings of the study and compares the hospital's rates of drug-resistant TB with previously reported rates, rates for other cities in New Jersey, and rates for the state.

摘要

自1986年(修订后的结核病[TB]监测病例定义实施后的第一个完整年份)起,新泽西州每10万人中报告的结核病发病率从9.5例增至1992年的12.6例。1992年向疾病控制与预防中心(CDC)报告的来自新泽西州的984例病例中,有108例(11.0%)来自泽西城(1990年人口:230,300)——该市报告的结核病病例数在该州排名第二,结核病发病率排名第四(每10万人中46.9例)。此外,1992年,新泽西州结核病患者中的耐多药结核病(MDR-TB)(即结核分枝杆菌分离株至少对异烟肼[INH]和利福平[RIF]耐药)发病率为5%;泽西城的发病率为13%。为了描述耐多药结核病患者的流行病学特征,新泽西州卫生部和泽西城医疗中心传染病科对1990 - 1992年期间在该医院接受治疗的患者进行了一项研究。本报告介绍了该研究的结果,并将该医院的耐多药结核病发病率与先前报告的发病率、新泽西州其他城市的发病率以及该州的发病率进行了比较。

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