Liappis N, Jäkel A
Klin Padiatr. 1976 May;188(3):267-70.
By the aid of the radial immunodiffusion method immunoglobulin G and albumin concentration were determined in cerebrospinal fluid of 58 boys and 47 girls (ages 1 month - 14 years). On the basis of clinical criterions these children were considered to be "healthy". The total number of examined children was 1200.
The sex-specific investigation of the 1 month-2 years and the 2-14 years old children showed no statistical significant differences. But the agespecific investigation revealed that the immunoglobulin G concentration in the cerebrospinal fluid of the older girls was statistically significant higher as compared to the younger girls and that the albumin concentration in the cerebrospinal fluid of the older boys was statistically significant lower than in the younger boys. The immunoglobulin G/albumin quotient was statistically significant higher in the group of older girls as compared to the group of younger girls.
借助放射免疫扩散法，测定了58名男孩和47名女孩（年龄1个月至14岁）脑脊液中的免疫球蛋白G和白蛋白浓度。根据临床标准，这些儿童被认为是“健康的”。接受检查的儿童总数为1200名。
对1个月至2岁以及2至14岁儿童的性别特异性调查显示，无统计学显著差异。但年龄特异性调查显示，年龄较大女孩脑脊液中的免疫球蛋白G浓度与年龄较小女孩相比，具有统计学显著升高；年龄较大男孩脑脊液中的白蛋白浓度与年龄较小男孩相比，具有统计学显著降低。年龄较大女孩组的免疫球蛋白G/白蛋白商与年龄较小女孩组相比，具有统计学显著升高。
