Nordsletten L, Skjeldal S, Kirkeby O J, Ekeland A
Institute for Surgical Research, Rikshospitalet, The National Hospital, Oslo, Norway.
Acta Orthop Scand. 1994 Apr;65(2):191-4. doi: 10.3109/17453679408995432.
Tibial fractures in 7-week-old rats were fixed with intramedullary nails. After 25 days of healing the nails were removed and the tibiae loaded in vivo with intact soft tissues until refracture. The animals were tested in three-point anterior cantilever bending either during muscle contraction (n 8) or with relaxed muscles (n 8). Muscle contraction increased the ultimate bending moment by 84 percent, energy absorption by 108 percent, bending stiffness by 21 percent, and ultimate deflection by 49 percent.
对7周龄大鼠的胫骨骨折采用髓内钉固定。愈合25天后取出髓内钉，在保留完整软组织的情况下对胫骨进行体内加载直至再次骨折。在肌肉收缩状态下（n = 8）或肌肉松弛状态下（n = 8）对动物进行三点前悬臂弯曲试验。肌肉收缩使极限弯矩增加了84%，能量吸收增加了108%，弯曲刚度增加了21%，极限挠度增加了49%。
