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高钙尿症和甲状旁腺功能亢进中的肾结石病

[Nephrolithiasis in hypercalciuria and hyperparathyroidism].

作者信息

Rapado A, de la Calle H, Castrillo J M, Mancha A, Traba M L, Delatte L C

出版信息

MMW Munch Med Wochenschr. 1976 Jun 18;118(25):799-810.

PMID:819807
Abstract

In the group of 1635 patients with nephorolithiasis the authors found 16% with idiopathic hypercalciuria. They administered thiazide diuretics for 8 days as a test for the detection of masked hyperparathyroidism in idiopathic hypercalciuria. In 6 cases which were diagnosed in this manner, the existence of a parathyroidadenoma could be demonstrated by surgical operation. The hypercalciuria persisted after exstirpation of the tumor, in some cases the nephrolithiasis also remained active. the various pathogenetic mechanisms connected with these common diseases are discussed in relation to these results.

摘要

在1635例肾石病患者组中,作者发现16%患有特发性高钙尿症。他们给予噻嗪类利尿剂8天,作为检测特发性高钙尿症中隐匿性甲状旁腺功能亢进的试验。通过这种方式诊断出的6例患者中,手术证实存在甲状旁腺瘤。肿瘤切除后高钙尿症持续存在,在某些情况下肾结石也仍然活跃。结合这些结果讨论了与这些常见疾病相关的各种发病机制。

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