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高钙尿症和甲状旁腺功能亢进性肾石病

[Hypercalciuric and hyperparathyroid renal lithiasis].

作者信息

Rapado A, de la Calle H, Castrillo J M, Mancha A, Traba M L, Cifuentes Delatte L

出版信息

Minerva Med. 1976 Nov 14;67(55):3573-81.

PMID:995303
Abstract

Idiopathic hypercalciuria was noted in 10% of a series of 1635 subjects with renal lithiasis. Eight-day administration of thiazide diuretics as a test for the discovery of latent hyperparathyroidism in idiopathic hypercalciuria is described. In 6 cases diagnosed in this way, surgery disclosed the presence of a parathyroid adenoma. Resection was followed by persistent hypercalciuria and, in some instances, renal lithiasis activity. The pathogenesis of associations of these frequently observed diseases is examined.

摘要

在1635例肾结石患者中,10%被发现患有特发性高钙尿症。本文描述了使用噻嗪类利尿剂进行为期八天的给药试验,以发现特发性高钙尿症患者潜在的甲状旁腺功能亢进。通过这种方式诊断出的6例患者中,手术发现存在甲状旁腺腺瘤。切除术后仍持续存在高钙尿症,在某些情况下,肾结石活动仍会出现。本文还探讨了这些常见疾病关联的发病机制。

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