Blumenthal S G, Ikeda R M, Ruebner B H
Pediatr Res. 1976 Jul;10(7):664-8. doi: 10.1203/00006450-197607000-00007.
Meconium of human infants and rhesus monkey infants (Macaca mulatta) contained only about 0.10 of the amount of bilirubin in gallbladder bile of the same individuals. Ninety-nine percent of the bilirubin in adult bile was conjugated. The proportion of conjugated bilirubin in infant bile and meconium was only slightly lower. Adult bile contained more bilirubin disconjugates than monoconjugates, whereas only 20% of the bilirubin in infant bile and meconium was in the form if disconjugates. The predominant azopigment in adult bile was azopigment delta (a glucuronide). Infant bile contained less azopigment delta, more azopigment alpha (azodipyrrole), and a so far unidentified conjugated azopigment (azopigment beta). Azopigment beta was also found in meconium but adult gallbladder bile contained only trace amounts of this pigment.
人类婴儿和恒河猴婴儿（猕猴）的胎粪中胆红素含量仅约为同一婴儿胆囊胆汁中胆红素含量的0.10。成年胆汁中99%的胆红素是结合型的。婴儿胆汁和胎粪中结合胆红素的比例仅略低。成年胆汁中所含的胆红素双结合物比单结合物更多，而婴儿胆汁和胎粪中只有20%的胆红素呈双结合物形式。成年胆汁中主要的偶氮色素是偶氮色素δ（一种葡糖醛酸苷）。婴儿胆汁中偶氮色素δ含量较少，偶氮色素α（偶氮二吡咯）较多，还有一种迄今未鉴定的结合偶氮色素（偶氮色素β）。在胎粪中也发现了偶氮色素β，但成年胆囊胆汁中仅含有痕量的这种色素。
