Basal cell and squamous cell carcinomas.

Basal cell and squamous cell carcinomas are actinic lesions that must be considered in the differential diagnosis of growths of the eyelid. Basal cell carcinoma is the most common eyelid cancer. It tends to grow slowly, and rarely if ever metastasizes. Basal cell carcinoma can, however, grow by direct extension to adjacent structures including the brain. Basal cell carcinoma can be managed by Moh's surgery, excision, cryosurgery, radiation, and chemotherapy. Squamous cell carcinoma has similar epidemiology to basal cell carcinoma. However, it grows much faster and it can metastasize (up to 20% of the time). It is best managed by conventional surgery, cryosurgery, and sometimes radiation. Squamous cell carcinoma can have a grim prognosis if not detected and treated promptly.