Fan S Z, Cheng Y J, Liu C C
Department of Anesthesiology, National Taiwan University Hospital, Taipei, R.O.C.
Acta Anaesthesiol Sin. 1994 Mar;32(1):51-6.
Fluctuations in heart rate (HR) and arterial blood pressure occurring at respiratory and lower frequencies have long been recognized. However, their significance remained obscure until the monitoring of fetal heart-rate variability (HRV) was appreciated. Recent studies suggest that HRV may reflect the sympatho-vagal interactions that modulate cardiovascular function. Analysis of HRV can provide a noninvasive measure of central autonomic outflow and autonomic reflex functions. A mathematical and signal-processing technique called power spectral analysis (PSA) has been used extensively to quantify HRV. Several frequencies of HR oscillations can be quantified: the low-frequency peak (LFP 0-0.04 Hz), the mid-frequency peak (MFP 0.05-0.15 Hz) and the high-frequency peak (HFP 0.15-0.4 Hz). In this review article, the physiological origins of these HR fluctuations are described and the changes of HRV by different pathophysiological states are also discussed. In conclusion, spectral analysis of HRV may provide important insights regarding the influence of anesthesia on cardiovascular neural control and anesthetic depth and the monitoring may be developed as a very useful non-invasive tool for modern anesthesia in the near future.
呼吸频率及更低频率下出现的心率（HR）和动脉血压波动早已为人所知。然而，在胎儿心率变异性（HRV）监测受到重视之前，它们的意义一直不明。近期研究表明，HRV可能反映调节心血管功能的交感 - 迷走神经相互作用。HRV分析能够提供一种非侵入性的中枢自主神经输出和自主神经反射功能测量方法。一种名为功率谱分析（PSA）的数学和信号处理技术已被广泛用于量化HRV。HR振荡的几个频率可以被量化：低频峰值（LFP 0 - 0.04Hz）、中频峰值（MFP 0.05 - 0.15Hz）和高频峰值（HFP 0.15 - 0.4Hz）。在这篇综述文章中，描述了这些HR波动的生理起源，并且也讨论了不同病理生理状态下HRV的变化。总之，HRV的频谱分析可能为麻醉对心血管神经控制和麻醉深度的影响提供重要见解，并且在不久的将来，这种监测可能会发展成为现代麻醉中一种非常有用的非侵入性工具。
