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[1988年至1992年采用局部β射线(钌106/铑106)治疗脉络膜恶性黑色素瘤的结果]

[Results of treatment of malignant melanoma of the choroid using local beta-irradiation (Ru106/Rh106) from 1988 to 1992].

作者信息

Oláh Z, Furdová A

机构信息

Klinika oftalmológie LF UK, Bratislava.

出版信息

Cesk Oftalmol. 1994 Apr;50(2):76-85.

PMID:8200050
Abstract

In the work results of focused, local therapy of the MMU (localised at choroidea) in the years 1988-92, with episclerally fixed applicators of the beta-emittors Ru106/Rh106 are presented. After this, so called "brachytherapy" (without enucleation), the group of 17 eyes (treated 18 times) was evaluated 18-54 months after therapy. Favourable results of treatment of the MMU at choroidea (small and localised) with episcleral, focused beta-radiation are emphasised. Up to December 31, 1992 at the group of 17 eyes healed MMU of the choroidea showed 58.8% of treated patients. Effective visual acuity (between 0.4-1.0) was preserved in 66.6% of the eyes. Exitus due to metastases occurred in 5 patients (24-48 month after therapy) showing the mortality rate 29.4%. These results are comparable with published statistics.

摘要

本文介绍了1988 - 1992年间,使用巩膜固定的β射线发射体Ru106/Rh106敷贴器对脉络膜黑色素瘤(MMU,位于脉络膜)进行局部聚焦治疗的工作成果。在进行了所谓的“近距离放射治疗”(未行眼球摘除术)后,对17只眼(共治疗18次)在治疗后18 - 54个月进行了评估。强调了采用巩膜聚焦β射线对脉络膜小范围局限性MMU进行治疗的良好效果。截至1992年12月31日,在17只脉络膜MMU治愈的眼中,治疗患者的比例为58.8%。66.6%的眼睛保留了有效视力(0.4 - 1.0之间)。5例患者(治疗后24 - 48个月)因转移而死亡,死亡率为29.4%。这些结果与已发表的统计数据相当。

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