Dramatic increase in levels of placental protein 14 in amniotic fluid at 10-15 weeks' pregnancy.
作者信息
Chatzakis K, Wathen N, Campbell J, Iles R, Dawnay A, Chard T
机构信息
Department of Obstetrics, Gynaecology and Reproductive Physiology, St. Bartholomew's Hospital Medical College, West Smithfield, London, UK.
出版信息
Early Hum Dev. 1994 Feb;36(2):113-6. doi: 10.1016/0378-3782(94)90038-8.
PMID:8200319
Abstract
Concentrations of placental protein 14 (PP14) were measured by radioimmunoassay in 103 amniotic fluid samples from 10 to 20 weeks of pregnancy. Low levels of PP14 were present at 10-12 weeks (median values 82-280 micrograms/l). After 12 weeks, the levels increased by two orders of magnitude to reach a peak at 18 weeks (median 11 mg/l). This pattern may reflect the obliteration of the extraembryonic coelom and direct apposition of the decidua with the chorio-amnion.
摘要
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