Arielly J, Weinberg D, Eliraz A, Adam M, el-Hanani B I, Eisenkraft S
Urology Dept., Kaplan Hospital, Rehovot.
Harefuah. 1994 Apr 1;126(7):369-73, 426.
34 impotent patients were offered auto-injection therapy and all except 2 began treatment. Prostaglandin E1 (PGE) was used regularly for a mean of 8.6 months (range 1-17). The onset of erection was 5-30 min (mean 11.4) after injection and it lasted at least 30 min (mean 106.2 min). An erection of more than 6 hrs was observed in only 2 patients. There have been no instances of cavernous fibrosis, chemical priapism or systemic reactions. The most common adverse effect was penile pain after injection. It was mild to moderate in 4 patients (11.7%), and in only 1 was it severe enough to require stopping treatment. Overall, intracavernous injection of PGE appears to be safe, effective treatment for impotence without side-effects other than pain after injection in a few.
34名阳痿患者接受了自我注射疗法，除2人外其余均开始治疗。前列腺素E1（PGE）被常规使用，平均使用时间为8.6个月（范围1 - 17个月）。注射后勃起开始时间为5 - 30分钟（平均11.4分钟），勃起持续至少30分钟（平均106.2分钟）。仅2例患者出现勃起超过6小时的情况。未发生海绵体纤维化、化学性阴茎异常勃起或全身反应。最常见的不良反应是注射后阴茎疼痛。4例患者（11.7%）疼痛为轻至中度，仅1例严重到需要停止治疗。总体而言，海绵体内注射PGE似乎是一种安全、有效的阳痿治疗方法，除少数患者注射后疼痛外无其他副作用。
