Tang S F, Chu N K, Wong M K
Department of Rehabilitation Medicine, Chang Gung Memorial Hospital, Taipei, Taiwan, Republic of China.
Paraplegia. 1995 Dec;33(12):731-3. doi: 10.1038/sc.1995.153.
Our experience with intracavernous injection of prostaglandin E1 in spinal cord injured patients with neurogenic erectile dysfunction included 15 men. They received testing dosage starting from 5 micrograms with increasing dosage (maximum 20 micrograms) to achieve a rigid erection of Schramek's grade 5 and lasting for at least 20 min. All of them had achieved functional erection adequate for coitus after treatment except one patient who had been proved to have venogenic impotence. We found that intracavernous injection of prostaglandin E1 had significantly improved the erectile condition. No systemic side effect or any other complication was noted except that pain at the injection site was complained of in two patients with incomplete lesion.
我们对15名患有神经源性勃起功能障碍的脊髓损伤患者进行阴茎海绵体内注射前列腺素E1的经验如下。他们从5微克的测试剂量开始，逐渐增加剂量（最大20微克），以达到施拉梅克5级的坚硬勃起，并持续至少20分钟。除一名被证实患有静脉性阳痿的患者外，所有患者在治疗后均实现了足以进行性交的功能性勃起。我们发现阴茎海绵体内注射前列腺素E1显著改善了勃起状况。除两名不完全性损伤患者抱怨注射部位疼痛外，未观察到全身副作用或任何其他并发症。
